You laugh. You frown. You concentrate. And over time, those expressions leave their mark upon your face. Until today, there wasn’t a lot you could do about it.

But today there’s BOTOX® Cosmetic. A simple, non-surgical procedure that can dramatically reduce even your toughest wrinkle within days. One ten-minute treatment-a few tiny injections-relaxes the muscles between your brows that cause lines to form. And keeps them relaxed up to four months.

Collagen Injections

"Radiance" consists of calcium hydroxylapatite suspended in gel (carboxymethylcellulose). Because calcium hydroxylapatite is a normal constituent of bone, it should not elicit a chronic inflammatory or immune response. Additionally, the gel carrier doesn't require allergy testing (such as required with collagen).

Calcium hydroxylapatite has been used in humans for a long time in prosthetic implants in dental, facial, and orthopedic surgery. Animal studies and use of the injectable product in vocal cords and bladder neck areas have shown that the product remains soft without new bone formation when injected into soft tissue. The longest term studies come from Italy which suggest that "Radiance" shows promise as a new agent for facial contouring with no serious side effects and reasonable efficacy and durability.

"Radiance" is not yet approved by the FDA for aesthetic uses, but approval is expected in the fall of 2002.